pentobarbital will lessen the extent or result of buprenorphine buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will lessen the extent or effect of armodafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.pentobarbital will lessen the extent or outcom